Upcoming Isoflurane Testing

Sentry Air Systems will be conducting efficiency testing on our Ductless Fume Hoods for use during applications involving the chemical Isoflurane. A third-party, independent safety expert and analyzing laboratory will be utilized. [The Results are Now In!

Isoflurane

As defined by the Environment, Health & Safety Department at UCLA, “Isoflurane (Forane, 1-chloro-2,2,2-trifluoroethyldifluoromethyl ether) is a halogenated hydrocarbon that is clear, colorless, volatile liquid at ordinary temperature and pressure. It has a mild, ether-like odor.” [1]

When vaporized, Isoflurane is used as an inhalational anesthesia to depress the central nervous system which results in loss of consciousness. This chemical is very frequently used in veterinary practice and many of Sentry Air’s clients have used our Ductless Fume Hoods to contain this chemical during this particular application.

Health Effects

Potential health effects of exposure to Isoflurane include “irritation of eyes, skin, respiratory tract; cough, sore throat; headache, drowsiness, dizziness; asphyxia; unconsciousness.” [2] Chronic exposure may lead to “hypotension, tachycardia, respiratory depression, and elevated blood glucose levels.” [1]

OSHA

The Occupational Safety & Health Administration does not have any permissible exposure limits (PEL) that regulate halogenated agents, however; it is recommended by NIOSH (The National Institute for Occupational Safety & Health) that “no worker should be exposed at ceiling concentrations greater than 2 ppm of any halogenated anesthetic agent over a sampling period not to exceed one hour.” [3] OSHA also recommends several engineering controls and work practices here.

Sentry Air’s Ductless Fume Hoods have had great success in containing Isoflurane during veterinary anesthesia applications and we continue to receive more and more phone calls regarding this equipment. Because of this elevated interest, we are requesting the consulting services of an independent, third-party safety expert and analyzing laboratory to present you with quantitative evidence of the effectiveness of Sentry Air’s Fume Hoods during this application.

Testing will begin soon and we will keep you posted with the results!

In the meantime, take a look at our Ductless Fume Hood Series here.

References

[1] UCLA EH&S, “Isoflurane Fact Sheet” <http://biosafety.ucla.edu/docs/factsheet%20isoflurane.pdf>

[2] OSHA, “Chemical Sampling Information: Isoflurane” <http://www.osha.gov/dts/chemicalsampling/data/CH_247970.html>

[3] OSHA, “Anesthetic Gases: Guidelines for Workplace Exposures” <http://www.osha.gov/dts/osta/anestheticgases/index.html#C2>