{"id":3678,"date":"2013-10-08T15:45:02","date_gmt":"2013-10-08T15:45:02","guid":{"rendered":"http:\/\/sentryair.com\/blog\/?p=3678"},"modified":"2020-06-25T20:08:43","modified_gmt":"2020-06-25T20:08:43","slug":"reducing-exposure-to-airborne-hormones-during-compounding","status":"publish","type":"post","link":"https:\/\/www.sentryair.com\/blog\/product-review\/fume-hoods\/ductless-fume-hood\/reducing-exposure-to-airborne-hormones-during-compounding\/","title":{"rendered":"Reducing Exposure to Airborne Hormones during Compounding"},"content":{"rendered":"<a href=\"https:\/\/www.sentryair.com\/blog\/wp-content\/uploads\/2013\/10\/DSC_0758.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-3680 \" title=\"Pharmaceutical Compounding\" src=\"https:\/\/www.sentryair.com\/blog\/wp-content\/uploads\/2013\/10\/DSC_0758-200x300.jpg\" alt=\"Pharmaceutical Powder Containment Hood\" width=\"154\" height=\"231\" srcset=\"https:\/\/www.sentryair.com\/blog\/wp-content\/uploads\/2013\/10\/DSC_0758-200x300.jpg 200w, https:\/\/www.sentryair.com\/blog\/wp-content\/uploads\/2013\/10\/DSC_0758.jpg 648w\" sizes=\"(max-width: 154px) 100vw, 154px\" \/><\/a>\n<p>Hormone therapy is commonly used to treat menopause symptoms in women. Though research into hormone therapy and its long term health effects have posed differing results over time, it is still a popular option to many who are looking to ease the symptoms of menopause.<\/p>\n<p>One treatment for hormone therapy is the use of pharmaceutical compounding.<\/p>\n<p>The Federal Drug Administration (FDA) regards traditional pharmacy compounding as &#8220;the combining or altering of ingredients by a pharmacist, in response to a licensed practitioner\u2019s prescription, to produce a drug tailored to an individual patient\u2019s special medical needs.&#8221;<\/p>\n<p>There are three major categories of FDA-approved menopausal hormone therapy products:<\/p>\n<ul>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Products containing only estrogen;<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 products containing only progestin;<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 and products containing estrogen and progestin<\/li>\n<\/ul>\n<p>You can view the complete list of the FDA-approved medications for menopause <a href=\"http:\/\/www.fda.gov\/ForConsumers\/ByAudience\/ForWomen\/ucm118627.htm\">here<\/a>.<\/p>\n<div id=\"attachment_3679\" style=\"width: 310px\" class=\"wp-caption alignright\"><a href=\"http:\/\/sentryair.com\/blog\/wp-content\/uploads\/2013\/10\/17amethyltestosterone.png\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-3679\" class=\"size-medium wp-image-3679\" title=\"17 a-methyltestosterone\" src=\"http:\/\/sentryair.com\/blog\/wp-content\/uploads\/2013\/10\/17amethyltestosterone-300x177.png\" alt=\"\" width=\"300\" height=\"177\" srcset=\"https:\/\/www.sentryair.com\/blog\/wp-content\/uploads\/2013\/10\/17amethyltestosterone-300x177.png 300w, https:\/\/www.sentryair.com\/blog\/wp-content\/uploads\/2013\/10\/17amethyltestosterone-500x295.png 500w, https:\/\/www.sentryair.com\/blog\/wp-content\/uploads\/2013\/10\/17amethyltestosterone.png 640w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><p id=\"caption-attachment-3679\" class=\"wp-caption-text\">17-a-methyltestosterone<\/p><\/div>\n<p><strong>Common ingredients found in hormone therapy.<\/strong><\/p>\n<p>Many brand name, over-the-counter, and specialty compounded hormone medicines contain these similar ingredients:<\/p>\n<ul>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Estradiol<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Estrone<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Estriol<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 17-\u03b1-methyltestosterone<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Progesterone<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Testosterone<\/li>\n<\/ul>\n<p>While these hormones are naturally occurring in the human body, at elevated levels they can be toxic and have carcinogenic effects.<\/p>\n<p><strong>The not-so hidden side effects for pharmacists.<\/strong><\/p>\n<p>Pharmacists, nurses, technicians, and others who prepare, handle and administer these medications may be exposed to significant health risks during the course of their work.<\/p>\n<p>A 2003 study published in the Oxford Journals on Occupational Medicine states &#8220;workers involved in the manufacture of drug substances can be exposed to active pharmaceutical ingredients (APIs) designed with the express intention of an interaction with the human system and modification of its functioning. Whilst such modification is generally desirable in patients, any modification in function, whether positive or negative, is an unacceptable outcome in the pharmaceutical industry worker.&#8221;<\/p>\n<p>Hazardous exposure to workers may occur through inhalation of dust created during the powder grinding, mixing and encapsulation processes.<\/p>\n<p>OSHA found three common examples that may present significant risks to the compounder, one of which is hormone medications. OSHA says &#8220;compounded hormone prescriptions may include hazardous ingredients, such as the hormones progesterone, testosterone, methyl testosterone, estradiol, and estriol.&#8221;<\/p>\n<p>Long term exposure to these hormones may cause an imbalance in levels resulting in adverse health effects.<\/p>\n<table border=\"1\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td valign=\"top\" width=\"175\">\n<p align=\"center\"><strong>Ingredient<\/strong><\/p>\n<\/td>\n<td valign=\"top\" width=\"415\">\n<p align=\"center\"><strong>Side Effects<\/strong><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"175\">\n<h6>Estradiol<\/h6>\n<\/td>\n<td valign=\"top\" width=\"415\">Causes human and animal mutations and has developmental reproductive effects.<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"175\">\n<h6>Estrone<\/h6>\n<\/td>\n<td valign=\"top\" width=\"415\">Reproductive effects include inhibition of egg implantation, suppression of spermatogenesis and impotence.<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"175\">\n<h6>Estriol<\/h6>\n<\/td>\n<td valign=\"top\" width=\"415\">A suspected carcinogen.<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"175\">\n<h6>17-\u03b1-Methyltestosterone<\/h6>\n<\/td>\n<td valign=\"top\" width=\"415\">A questionable human carcinogen, producing nonmalignant tumors in the liver.<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"175\">\n<h6>Progesterone<\/h6>\n<\/td>\n<td valign=\"top\" width=\"415\">Causes developmental abnormalities and has serious effects on males including impotence, breast enlargement and spermatogenesis.<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"175\">\n<h6>Testosterone<\/h6>\n<\/td>\n<td valign=\"top\" width=\"415\">Causes developmental changes in the urogenital system.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>How to reduce airborne hormone particles during compounding. <\/strong><\/p>\n<p>OSHA recommends that specific measures be implemented to: reduce direct skin contact; reduce exposure via inhalation; and minimize the possibility of chemicals being brought home on workers\u2019 clothing.<\/p>\n<p>Some examples include engineering controls (e.g., barriers and containments, laboratory hoods, glove boxes, and worker isolation); administrative controls; personal protective equipment (e.g., respirators, gloves and lab coats); and training.<\/p>\n<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignleft\" title=\"Pharmaceutical Compounding Hood\" src=\"http:\/\/www.sentryair.com\/images\/ss-224-dch4.jpg\" alt=\"\" width=\"333\" height=\"250\" \/>Ductless Powder Containment Hoods with HEPA Filtration<\/strong><\/p>\n<p>A ductless powder containment hood equipped with HEPA filtration is a portable, compact, and efficient solution to filtering renegade dust and powders during compounding.<\/p>\n<p>Sentry Air\u2019s <a href=\"http:\/\/www.sentryair.com\/pharmaceutical.htm\">Pharmaceutical Powder Containment Hoods<\/a>* utilize a powerful fan and filtration system that pulls harmful airborne powder and particulate away from the operator\u2019s breathing zone and directly into the HEPA filter, which is up to 99.97% efficient on particles 0.3 microns and larger.<\/p>\n<p>By adding clear anti-static vinyl strip curtains, you better enclose the face opening of the hood while still allowing easy access inside.<\/p>\n<p>Our containment hoods come in a variety of sizes and can be customized to your unique application. Most of our powder containment hoods are sized to work well with <a href=\"http:\/\/sentryair.com\/blog\/?s=torpac&amp;submit=Search\">Torpac<sup>\u00ae <\/sup>capsule fillers<\/a>.<\/p>\n<p>*<em>Our line of pharmaceutical powder containment hoods are not intended for sterile compounding applications.<\/em><\/p>\n<a href=\"https:\/\/www.sentryair.com\/powder-containment-hood.htm\" target=\"_blank\" rel=\"noopener noreferrer\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/www.sentryair.com\/blog\/wp-content\/uploads\/2020\/03\/SentryAirSystems-LearnMore-button.png\" alt=\"Learn More about Pharmaceutical Powder Containment Hoods\" width=\"150\" height=\"38\" \/><\/a>\n<p><strong>Contact Us!<\/strong><\/p>\n<p>If you compound hormone therapy treatments in your pharmacy or would like more information about the health benefits of powder containment hoods, contact Sentry Air today. Give us a call at 800.799.4609, email <a href=\"mailto:sales@sentryair.com\">sales@sentryair.com<\/a>, visit our website <a href=\"http:\/\/www.sentryair.com\/\">www.sentryair.com<\/a> or fill out the feedback form below.<\/p>\n<p><strong>Resources<\/strong><\/p>\n<ol>\n<li><a style=\"font-style: normal;\" href=\"http:\/\/www.fda.gov\/Drugs\/GuidanceComplianceRegulatoryInformation\/PharmacyCompounding\/ucm183088.htm\">http:\/\/www.fda.gov\/Drugs\/GuidanceComplianceRegulatoryInformation\/PharmacyCompounding\/ucm183088.htm<\/a><\/li>\n<li><a style=\"font-style: normal;\" href=\"https:\/\/www.osha.gov\/dts\/sltc\/methods\/partial\/pv2001\/2001.html\">https:\/\/www.osha.gov\/dts\/sltc\/methods\/partial\/pv2001\/2001.html<\/a><\/li>\n<li><a style=\"font-style: normal;\" href=\"http:\/\/www.fda.gov\/Drugs\/GuidanceComplianceRegulatoryInformation\/PharmacyCompounding\/default.htm\">FDA\u2019s pharmacy compounding Web page<\/a><span style=\"color: #333333; font-family: 'Helvetica Neue', Helvetica, Arial, 'Nimbus Sans L', sans-serif; font-style: normal;\">.<\/span><\/li>\n<li><a style=\"font-style: normal;\" href=\"https:\/\/www.osha.gov\/dts\/tib\/tib_data\/tib20011221.html\">https:\/\/www.osha.gov\/dts\/tib\/tib_data\/tib20011221.html<\/a><\/li>\n<li><a style=\"font-style: normal;\" href=\"http:\/\/occmed.oxfordjournals.org\/content\/53\/6\/357.full.pdf\">http:\/\/occmed.oxfordjournals.org\/content\/53\/6\/357.full.pdf<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Hormone therapy is commonly used to treat menopause symptoms in women. Though research into hormone therapy and its long term health effects have posed differing results over time, it is still a popular option to many who are looking to ease the symptoms of menopause. One treatment for hormone therapy is the use of pharmaceutical&#8230;  <a class=\"excerpt-read-more btn btn-primary\" style=\"display:block; color: #fff;  margin-top: 10px; max-width:120px;\" href=\"https:\/\/www.sentryair.com\/blog\/product-review\/fume-hoods\/ductless-fume-hood\/reducing-exposure-to-airborne-hormones-during-compounding\/\" title=\"Read Reducing Exposure to Airborne Hormones during Compounding\">Learn More<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[84,805,2448],"tags":[],"class_list":["post-3678","post","type-post","status-publish","format-standard","hentry","category-ductless-fume-hood","category-pharmaceutical","category-powder-containment-hood"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Reducing Exposure to Airborne Hormones during Compounding - Sentry Air Systems, Inc.<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.sentryair.com\/blog\/product-review\/fume-hoods\/ductless-fume-hood\/reducing-exposure-to-airborne-hormones-during-compounding\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Reducing Exposure to Airborne Hormones during Compounding - Sentry Air Systems, Inc.\" \/>\n<meta property=\"og:description\" content=\"Hormone therapy is commonly used to treat menopause symptoms in women. 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